In radiosurgery a moving beam of radiation is used as an ablative surgical instrument to destroy brain tumors. Classical radiosurgical systems rely on rigid skeletal fixation of the anatomic region to be treated. This fixation procedure is very painful for the patient and limits radiosurgical procedures to brain lesions. Furthermore, due to the necessity of rigid fixation, radiosurgical treatment with classical systems cannot be fractionated. A new {camera-guided radiosurgical system} \* link to neuro.ps *\ capable of tracking patient motion during treatment has been built to overcome these problems. The radiation source is moved by a six degree-of-freedom robotic arm. In addition to offering a more cost effective, less invasive, and less painful treatment, the robotic gantry allows for arbitrary spatial motion of the radiation source. Based on this feature we can treat non-spherical lesions with accuracies unachievable with classical radiosurgical systems. The system introduces a new class of radiosurgical procedures, called non-stereotactic, or image-guided radiosurgery. At the heart of these procedures are algorithms for planning both a treatment and the corresponding beam motion, given the geometric description of the tumor shape and relative locations in the particular case. Project Group: Achim Schweikard Rhea Tombropoulos Jean-Claude Latombe John Adler Departments of Neurosurgery and Robotics Laboratory, Department of Computer Science, Stanford University. Recent Publications Treatment Planning for a Radiosurgical System with General Kinematics, Proc. IEEE Conf. Robotics & Automation, 1994. Planning for Image Guided Radiosurgery AAAI Spring Symp. Medical Applications of Computer Vision, 1994.