Genes for module 172

LocusLinkNameP-valueDescription
4316MMP7<1e-14matrix metalloproteinase 7 (matrilysin, uterine).MMP-7; MPSL1; PUMP-1.matrix metalloproteinase 7 preproprotein.
3240HP<1e-14haptoglobin..haptoglobin.
290ANPEP<1e-14alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150).CD13; LAP1; PEPN; gp150.membrane alanine aminopeptidase precursor.
2028ENPEP<1e-14glutamyl aminopeptidase (aminopeptidase A).APA; gp160.glutamyl aminopeptidase (aminopeptidase A).
715C1R<1e-14complement component 1, r subcomponent..complement component 1, r subcomponent.
4318MMP9<1e-14matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase).GELB; CLG4B.matrix metalloproteinase 9 preproprotein.
716C1S<1e-14complement component 1, s subcomponent..complement component 1, s subcomponent.
1514CTSL<1e-14cathepsin L.MEP; CATL.cathepsin L preproprotein.
2147F2<1e-14coagulation factor II (thrombin).PT.coagulation factor II precursor.
344APOC2<1e-14apolipoprotein C-II..apolipoprotein C-II precursor.
1513CTSK<1e-14cathepsin K (pycnodysostosis).PKND; CTS02; CTSO1; CTSO2; MGC23107.cathepsin K preproprotein.
1369CPN1<1e-14carboxypeptidase N, polypeptide 1, 50kD.CPN; SCPN.carboxypeptidase N, polypeptide 1, 50kD precursor.
10406WFDC2<1e-14WAP four-disulfide core domain 2.HE4; WAP5; dJ461P17.6.WAP four-disulfide core domain 2 isoform 5.
165AEBP1<1e-14AE binding protein 1.ACLP.adipocyte enhancer binding protein 1 precursor.
4313MMP2<1e-14matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase).CLG4; CLG4A; TBE-1.matrix metalloproteinase 2 preproprotein.
5320PLA2G2A<1e-14phospholipase A2, group IIA (platelets, synovial fluid).MOM1; PLA2B; PLA2L; PLA2S; PLAS1.phospholipase A2, group IIA (platelets, synovial fluid).
5645PRSS2<1e-14protease, serine, 2 (trypsin 2).TRY2; TRY8; TRYP2.protease, serine, 2 preproprotein.
7176TPS1<1e-14tryptase, alpha.TPS2; alpha II.alpha tryptase I precursor.
2161F12<1e-14coagulation factor XII (Hageman factor).HAF.coagulation factor XII precursor.
6652SORD<1e-14sorbitol dehydrogenase.SORD1.sorbitol dehydrogenase.
5327PLAT<1e-14plasminogen activator, tissue.TPA; T-PA.plasminogen activator, tissue type isoform 3 precursor.
717C2<1e-14complement component 2.CO2.complement component 2 precursor.
4485MST1<1e-14macrophage stimulating 1 (hepatocyte growth factor-like).MSP; HGFL; NF15S2; D3F15S2; DNF15S2.macrophage stimulating 1 (hepatocyte growth factor-like).
7113TMPRSS2<1e-14transmembrane protease, serine 2.PRSS10.transmembrane protease, serine 2.
3003GZMK<1e-14granzyme K (serine protease, granzyme 3; tryptase II).PRSS; TRYP2.granzyme K precursor.
341APOC1<1e-14apolipoprotein C-I..apolipoprotein C-I precursor.
5340PLG<1e-14plasminogen..plasminogen.
1510CTSE<1e-14cathepsin E..cathepsin E isoform b preproprotein.
5652PRSS8<1e-14protease, serine, 8 (prostasin).PROSTASIN.prostasin preproprotein.
1361CPB2<1e-14carboxypeptidase B2 (plasma, carboxypeptidase U).CPU; PCPB; TAFI.plasma carboxypeptidase B2 isoform b.
8309ACOX2<1e-14acyl-Coenzyme A oxidase 2, branched chain.BCOX; BRCOX; BRCACOX.acyl-Coenzyme A oxidase 2, branched chain.
3479IGF1<1e-14insulin-like growth factor 1 (somatomedin C).IGFI.insulin-like growth factor 1 (somatomedin C).Insulin-like growth factor I (somatomedin C); activates cell proliferation and differentiation; strongly similar to murine Igf1|Proteome
3249HPN<1e-14hepsin (transmembrane protease, serine 1).TMPRSS1.hepsin (transmembrane protease, serine 1).
345APOC31.98952e-13apolipoprotein C-III..apolipoprotein C-III precursor.
4312MMP17.10543e-13matrix metalloproteinase 1 (interstitial collagenase).CLG; CLGN.matrix metalloproteinase 1 preproprotein.
5225PGC9.37916e-13progastricsin (pepsinogen C)..progastricsin (pepsinogen C).
570BAAT1.67688e-12bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase).BAT; BACAT.bile acid Coenzyme A: amino acid N-acyltransferase.
3002GZMB1.90425e-12granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1).HLP; CCPI; CGL1; CSPB; SECT; CGL-1; CSP-B; CTLA1; CTSGL1.granzyme B precursor.
5045FURIN2.75691e-12furin (paired basic amino acid cleaving enzyme).FUR; PACE; SPC1; PCSK3.furin preproprotein.
7076TIMP15.48539e-12tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor).EPA; EPO; HCI; CLGI; TIMP.tissue inhibitor of metalloproteinase 1 precursor.
3426IF7.36122e-12I factor (complement).FI.I factor (complement).
4314MMP32.11742e-11matrix metalloproteinase 3 (stromelysin 1, progelatinase).SL-1; STMY; STR1; STMY1; TRANSIN.matrix metalloproteinase 3 preproprotein.
5641LGMN3.11786e-11legumain.LGMN1; PRSC1.legumain.
629BF3.2486e-11B-factor, properdin.GBG; CFAB; PBF2.complement factor B preproprotein.
5336PLCG24.17515e-11phospholipase C, gamma 2 (phosphatidylinositol-specific)..phospholipase C, gamma 2 (phosphatidylinositol-specific).
1368CPM1.28153e-10carboxypeptidase M..carboxypeptidase M precursor.
2592GALT2.32259e-09galactose-1-phosphate uridylyltransferase..galactose-1-phosphate uridylyltransferase isoform 3.
8858PROZ4.65812e-09protein Z, vitamin K-dependent plasma glycoprotein.PZ.protein Z, vitamin K-dependent plasma glycoprotein.
4973OLR15.11093e-09oxidised low density lipoprotein (lectin-like) receptor 1.LOX1; SCARE1.oxidised low density lipoprotein (lectin-like) receptor 1.
5328PLAU7.97812e-09plasminogen activator, urokinase.UPA; URK.plasminogen activator, urokinase.
834CASP11.10889e-08caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase).ICE; P45; IL1BC.caspase 1 isoform gamma precursor.
1520CTSS1.9302e-08cathepsin S.MGC3886.cathepsin S preproprotein.
4322MMP133.247e-08matrix metalloproteinase 13 (collagenase 3).CLG3.matrix metalloproteinase 13 preproprotein.
837CASP41.90668e-07caspase 4, apoptosis-related cysteine protease.TX; ICH-2; Mih1TX; ICEREL-II; ICErel-II; ICE(rel)II.caspase 4 isoform gamma precursor.
4321MMP122.03409e-07matrix metalloproteinase 12 (macrophage elastase).HME; MME.matrix metalloproteinase 12 preproprotein.
2191FAP1.64986e-06fibroblast activation protein, alpha.FAPA; DPPIV; SEPRASE.fibroblast activation protein, alpha subunit.
110982.23083e-06ZSIG13; MGC5107; PRSS23-PENDING.protease, serine, 23 precursor.
2582GALE9.07709e-06galactose-4-epimerase, UDP-..UDP-galactose-4-epimerase.
94761.18166e-05NAPA.pronapsin A.
4069LYZ1.55685e-05lysozyme (renal amyloidosis)..lysozyme precursor.
649BMP11.98526e-05bone morphogenetic protein 1.TLD.bone morphogenetic protein 1 isoform 6 precursor.
3988LIPA3.3485e-05lipase A, lysosomal acid, cholesterol esterase (Wolman disease).LAL; CESD.lipase A precursor.
3001GZMA5.5771e-05granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3).HFSP; CTLA3.granzyme A precursor.
1359CPA35.9796e-05carboxypeptidase A3 (mast cell)..mast cell carboxypeptidase A3 precursor.
3990LIPC6.32188e-05lipase, hepatic.HL; HTGL; LIPH.lipase C precursor.
1636ACE6.44136e-05angiotensin I converting enzyme (peptidyl-dipeptidase A) 1.DCP; ACE1; DCP1; CD143; MGC26566.angiotensin I converting enzyme isoform 3 precursor.
10136ELA3A7.35846e-05elastase 3A, pancreatic (protease E).ELA3.elastase 3, pancreatic (protease E).
2159F100.00030086coagulation factor X.FX; FXA.coagulation factor X precursor.
51056LAP30.000384043leucine aminopeptidase 3.LAP; PEPS; LAPEP.leucine aminopeptidase.
3157HMGCS10.0004146713
1075CTSC0.00046854cathepsin C.HMS; PLS; CPPI; DPP1; DPPI; PALS.cathepsin C isoform b precursor.
3158HMGCS20.0005270033
4323MMP140.000629822matrix metalloproteinase 14 (membrane-inserted).MMP-X1; MTMMP1; MT1-MMP.matrix metalloproteinase 14 preproprotein.
5624PROC0.000847929protein C (inactivator of coagulation factors Va and VIIIa)..protein C (inactivator of coagulation factors Va and VIIIa).
5698PSMB90.00158012proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional protease 2).LMP2; RING12.proteasome beta 9 subunit isoform 2 proprotein.
10537UBD0.00186346ubiquitin D.FAT10.diubiquitin.
75130.00203412
726CAPN50.00242905calpain 5.HTRA3; nCL-3.calpain 5.
9588PRDX60.00305519peroxiredoxin 6.PRX; p29; AOP2; 1-Cys; NSGPx; aiPLA2; KIAA0106; MGC46173.peroxiredoxin 6.
1519CTSO0.00311598cathepsin O.CTSO1.cathepsin O preproprotein.
8754ADAM90.00378689a disintegrin and metalloproteinase domain 9 (meltrin gamma).MCMP; MDC9; Mltng; KIAA0021.a disintegrin and metalloproteinase domain 9 preproprotein.
824CAPN20.00461922calpain 2, (mII) large subunit.mCANP; CANPL2; CANPml.calpain 2, large subunit.
7941PLA2G70.00465134phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma).PAFAH; LDL-PLA2.phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma).
4324MMP150.00471155matrix metalloproteinase 15 (membrane-inserted).MTMMP2; SMCP-2; MT2-MMP.matrix metalloproteinase 15 preproprotein.
4738NEDD80.00517541neural precursor cell expressed, developmentally down-regulated 8.Nedd-8.neural precursor cell expressed, developmentally down-regulated 8.
5655KLK100.00571172kallikrein 10.NES1; PRSSL1.kallikrein 10 precursor.
95ACY10.005836aminoacylase 1.ACYLASE.aminoacylase 1.
5184PEPD0.00691064peptidase D.MGC10905; PROLIDASE.Xaa-Pro dipeptidase.
4320MMP110.0083084matrix metalloproteinase 11 (stromelysin 3).ST3; SL-3; STMY3.matrix metalloproteinase 11 preproprotein.
1118CHIT10.0106798chitinase 1 (chitotriosidase).CHIT.chitotriosidase.
1509CTSD0.0116665cathepsin D (lysosomal aspartyl protease).CPSD; MGC2311.cathepsin D preproprotein.
1508CTSB0.0222214cathepsin B.APPS; CPSB.cathepsin B preproprotein.
7915ALDH5A10.0230697aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase).SSDH; SSADH.aldehyde dehydrogenase 5A1 precursor isoform 2.
2346FOLH10.0267428folate hydrolase (prostate-specific membrane antigen) 1.PSM; FOLH; GCP2; PSMA; NAALAD1; NAALAdase.folate hydrolase (prostate-specific membrane antigen) 1.
1803DPP40.0350191dipeptidylpeptidase 4 (CD26, adenosine deaminase complexing protein 2).CD26; ADABP; ADCP2; DPPIV; TP103.dipeptidylpeptidase IV.
5653KLK60.0356731kallikrein 6 (neurosin, zyme).SP59; PRSS9; MGC9355; NEUROSIN.kallikrein 6 preproprotein.