Module 507

Jump to: General properties | Gene sets | Enriched clinical annotations | Enriched Go annotations | Visual display
General Properties
Below we list the number of gene sets from which the module was composed was originally composed, and the number of genes and experiments that it contains. Clicking on the number of genes will display a detailed list of all the genes in the module. Clicking on the number of experiments will display a detailed list of all the experiments in the module.
Num gene sets: 2
Num genes: 42 (see 46 additional genes for this module)
Num experiments: 91 (25 induced, 66 repressed)


Jump to: General properties | Gene sets | Enriched clinical annotations | Enriched Go annotations | Visual display
Gene sets
Below we list the gene sets from which the module was originally composed. Clicking on a gene set will display all the genes associated with that gene set. Also listed are all the other modules in which the gene set participates.
protein complex assembly 507
Rosenwald01 44 507


Jump to: General properties | Gene sets | Enriched clinical annotations | Enriched Go annotations | Visual display
Enriched clinical annotations
For each of the clinical annotations, we tested whether it was enriched in the set of experiments in which the module is significantly induced (or repressed). Below we list all such annotations that were enriched in this module with an FDR corrected p-value of 0.05 ('P-value' column), along with the number ('Hits' column) of induced (or repressed) experiments in which they appear. We also show the fraction of experiments with the given annotation that are included in this module ('Hits (%)' column). Rows that correspond to annotations that were enriched in the induced experiments of the module have a red background, while rows corresponding to annotations enriched in the repressed experiments have a green background. For each annotation, we also list the other modules in which it was enriched.
Clinical annotation P-value Hits Hits(%) Modules
Melanoma tumor or cell line 1.98e-06 7 10.606 14 18 55 68 88 139 178 180 220 297 298 335 342 362 402 418 444 455 491 492 507 568
Fast doubling (20-40) cell lines 4.82e-06 13 19.696 1 2 5 6 11 12 14 15 19 23 24 33 38 44 45 46 47 55 60 66 75 79 84 88 100 112 119 122 128 137 139 154 170 176 178 180 213 220 227 292 297 321 335 342 357 362 418 426 444 455 474 491 492 493 505 507 513 515 516 549 568
Cell line 5.46e-06 26 39.393 3 9 14 18 52 54 57 85 118 119 124 139 147 153 161 178 180 192 195 198 199 227 244 252 256 279 283 302 315 321 333 334 335 356 362 394 397 403 405 406 418 426 427 444 451 455 480 485 492 493 503 505 507 513 516 561 576
Liver tissue 6.20e-06 11 44 1 2 3 5 6 8 9 10 11 12 15 16 17 18 19 23 24 26 27 33 34 38 40 41 43 44 45 46 47 48 49 52 53 54 55 57 58 60 63 64 66 67 73 75 76 78 79 84 85 88 92 93 94 95 96 98 99 100 101 106 107 108 109 112 117 118 121 122 123 125 128 129 130 131 132 134 135 137 139 140 143 146 154 158 162 163 164 165 170 171 172 176 180 184 185 186 190 191 193 197 198 199 205 207 208 209 212 213 220 221 223 227 234 235 236 239 247 248 249 251 252 253 257 259 262 263 265 286 287 288 289 292 293 294 295 297 305 306 309 310 315 320 321 324 327 335 337 342 343 345 349 353 354 357 364 367 370 372 373 375 385 386 397 401 404 405 406 410 415 417 422 423 424 426 432 434 436 437 440 445 452 458 461 468 469 474 477 478 479 481 484 485 486 495 496 505 506 507 510 514 515 523 528 529 530 536 544 545 546 553 556 564 566
Hepatitis infected 9.03e-06 10 40 1 2 5 6 8 9 10 11 12 15 17 19 23 24 27 33 34 38 40 41 43 44 45 46 47 48 49 52 53 54 55 57 58 60 63 64 66 67 73 75 76 78 79 84 85 88 92 93 94 95 96 98 99 100 101 106 107 108 109 112 117 118 121 123 125 128 129 130 131 132 134 135 137 140 144 146 154 158 163 164 165 170 171 172 176 180 184 185 190 191 193 197 198 199 205 207 208 209 212 213 221 223 227 234 235 239 247 248 249 251 252 257 259 262 263 265 276 286 287 288 289 292 293 294 295 297 305 306 309 310 319 320 324 327 337 342 343 345 349 353 354 357 364 367 370 372 373 375 385 386 397 401 404 406 410 415 417 422 423 424 426 434 436 440 445 452 458 461 468 469 474 477 478 479 481 485 486 495 496 505 506 507 510 514 515 523 529 530 536 544 545 546 553 564 566
Liver tissue or cell line 1.04e-05 11 44 1 2 3 5 6 8 9 10 11 12 15 16 17 18 19 23 24 27 33 34 38 40 41 43 44 45 46 47 48 49 52 53 54 55 57 58 60 63 64 66 67 72 73 75 76 78 79 84 85 88 92 93 94 95 96 98 99 100 101 106 107 108 109 112 117 118 121 122 123 125 128 129 130 131 132 134 135 137 139 140 146 154 158 162 163 164 165 170 171 172 176 180 184 185 186 190 191 193 197 198 199 205 207 208 209 212 213 220 221 223 227 234 235 236 239 247 248 249 250 251 252 253 257 259 262 263 265 283 286 287 288 289 292 293 294 295 297 305 306 309 310 315 320 321 324 327 335 337 342 343 345 349 353 354 357 364 367 370 372 373 375 385 386 397 401 402 404 405 406 410 415 417 422 423 424 426 432 434 436 437 440 445 452 454 457 458 461 468 469 474 477 478 479 481 484 486 495 496 505 506 507 510 514 515 523 528 529 530 536 544 545 546 553 556 564 566
HCC 2.49e-05 8 32 3 8 9 10 15 16 17 18 19 23 24 27 40 41 43 44 47 48 49 52 53 54 55 57 58 63 64 67 72 76 78 88 90 92 93 95 98 99 101 106 108 117 118 123 125 129 130 132 135 137 140 143 144 154 158 162 163 164 165 171 172 180 184 185 189 190 193 198 205 207 208 209 212 221 223 234 235 239 247 249 251 252 257 259 263 286 289 292 293 294 295 305 306 309 310 337 342 343 345 353 354 367 372 373 375 391 394 397 415 421 422 424 432 436 440 452 458 469 470 474 478 479 481 486 495 505 506 507 510 514 515 523 526 536 543 544 545 553 566 573
HBV infected 4.11e-05 9 36 1 2 5 6 8 9 10 11 12 15 17 18 19 23 24 27 33 34 38 40 41 43 44 45 46 47 48 49 52 53 54 55 57 58 60 63 64 66 67 73 75 76 78 84 85 88 92 93 94 95 96 98 99 100 101 106 107 108 109 112 117 118 121 123 125 129 130 131 132 134 135 137 140 144 146 154 158 163 164 165 172 176 180 184 185 190 191 193 197 198 199 205 207 209 212 213 221 223 227 234 235 239 247 248 249 251 252 257 259 262 263 265 276 286 287 288 289 292 293 294 295 297 305 306 309 310 319 320 324 327 337 342 343 345 349 353 354 357 364 367 370 372 373 375 385 386 397 401 404 406 410 415 417 422 423 424 426 432 434 436 440 445 452 458 461 468 469 474 477 478 479 481 485 486 495 496 505 506 507 510 514 515 523 529 530 536 544 545 546 553 566
Melanocytes: normal or cell line 0.00012 5 7.575 14 18 139 178 180 220 297 335 342 346 357 362 390 402 418 426 433 444 455 491 492 507 568
Melanoma cell line 0.00012 5 7.575 14 18 139 178 180 220 297 335 342 346 357 362 390 402 418 426 433 444 455 491 492 507 568
Renal cell line 0.00017 5 7.575 178 227 321 335 362 426 444 507
Renal tumor or cell line 0.00030 6 9.090 11 178 213 227 321 335 362 444 507


Jump to: General properties | Gene sets | Enriched clinical annotations | Enriched Go annotations | Visual display
Enriched GO annotations
For each GO annotation, we tested whether it was enriched in the set of genes of the module. Below we list all such annotations that were enriched in this module with an FDR corrected p-value of 0.05 ('P-value' column), along with the number ('Hits' column) of genes in which they appear. We also show the fraction of genes with the given GO annotation that are included in this module ('Hits (%)' column).


Jump to: General properties | Gene sets | Enriched clinical annotations | Enriched Go annotations | Visual display
Visual display
Below is a visual display of the module. Shown are those arrays in which the module's genes significantly change, and the direction of change (induction/repression) in each array is indicated (middle, labeled 'Module changes'; red/green row). The arrays that correspond to the significant clinical attributes are also shown (top; brown rows). The gene sets that compose the module are also shown (left) along with an indication of the membership of the module genes in these gene sets.
You can also view the images within GeneXPress by loading the module gxp file file.
 
 





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