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 >4x |
Module 472 |
| General Properties | |
|---|---|
| Below we list the number of gene sets from which the module was composed was originally composed, and the number of genes and experiments that it contains. Clicking on the number of genes will display a detailed list of all the genes in the module. Clicking on the number of experiments will display a detailed list of all the experiments in the module. | |
| Num gene sets: | 2 |
| Num genes: | 11 (see 805 additional genes for this module) |
| Num experiments: | 22 (15 induced, 7 repressed) |
| Gene sets | |
|---|---|
| Below we list the gene sets from which the module was originally composed. Clicking on a gene set will display all the genes associated with that gene set. Also listed are all the other modules in which the gene set participates. | |
| GPCRs, Class A Rhodopsin_like 2 | |
| perception of mechanical stimulus | 472 571 |
| Enriched clinical annotations | ||||
|---|---|---|---|---|
| For each of the clinical annotations, we tested whether it was enriched in the set of experiments in which the module is significantly induced (or repressed). Below we list all such annotations that were enriched in this module with an FDR corrected p-value of 0.05 ('P-value' column), along with the number ('Hits' column) of induced (or repressed) experiments in which they appear. We also show the fraction of experiments with the given annotation that are included in this module ('Hits (%)' column). Rows that correspond to annotations that were enriched in the induced experiments of the module have a red background, while rows corresponding to annotations enriched in the repressed experiments have a green background. For each annotation, we also list the other modules in which it was enriched. | ||||
| Clinical annotation | P-value | Hits | Hits(%) | Modules |
| Alive - Lung cancer | 7.19e-07 | 4 | 26.666 | 2 6 23 38 44 45 46 55 60 64 75 88 94 107 139 153 154 165 172 180 209 213 223 297 342 357 472 |
| Grade 3- lung | 3.87e-06 | 4 | 26.666 | 2 9 23 24 33 38 45 48 55 88 95 101 122 139 163 172 176 180 220 230 234 280 297 324 326 342 357 472 486 |
| Good prognosis 2 - AD | 1.25e-05 | 3 | 20 | 38 154 165 172 297 357 373 472 |
| Enriched GO annotations | ||||
|---|---|---|---|---|
| For each GO annotation, we tested whether it was enriched in the set of genes of the module. Below we list all such annotations that were enriched in this module with an FDR corrected p-value of 0.05 ('P-value' column), along with the number ('Hits' column) of genes in which they appear. We also show the fraction of genes with the given GO annotation that are included in this module ('Hits (%)' column). | ||||
| GO annotation | P-value | Hits | Hits(%) | |
| response to mechanical stimulus | 2.84e-16 | 6 | 54.545 | |
| rhodopsin-like receptor activity | 3.49e-12 | 8 | 72.727 | |
| sensory perception | 5.04e-11 | 11 | 100 | |
| G-protein coupled receptor protein signaling pathway | 4.95e-10 | 8 | 72.727 | |
| conjugation without cellular fusion | 4.85e-08 | 6 | 54.545 | |
| transmembrane receptor activity | 6.42e-08 | 8 | 72.727 | |
| receptor activity | 8.43e-07 | 8 | 72.727 | |
| signal transducer activity | 4.58e-06 | 9 | 81.818 | |
| cytosolic calcium ion concentration elevation | 5.10e-06 | 3 | 27.272 | |
| G-protein signaling\, coupled to IP3 second messenger (phospholipase C activating) | 4.50e-05 | 3 | 27.272 | |
| peptide receptor activity | 4.77e-05 | 3 | 27.272 | |
| Visual display | |||||||||
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| Below is a visual display of the module. Shown are those arrays in which the module's genes significantly change, and the direction of change (induction/repression) in each array is indicated (middle, labeled 'Module changes'; red/green row). The arrays that correspond to the significant clinical attributes are also shown (top; brown rows). The gene sets that compose the module are also shown (left) along with an indication of the membership of the module genes in these gene sets. | |||||||||
| You can also view the images within GeneXPress by loading the module gxp file file. | |||||||||
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