Modules    GeneXPress

   Global Analysis (Fig. 3)    Experimental Tests    Candidate Regulators

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   Supplemental Information

Experimental Tests

There were quite a few modules for which the predicted regulators are not well characterized. In some of these cases, the expression of the regulator was induced. This suggests knock out experiements where we measure the expression of genes in a strain lacking the regulator under the same experimental conditions in which the program predicted regulation. We performed some of these experiments. For each experiment, the data is avilable for download. In addition, we show graphs of the expression of all genes in the WT compared to the KO. We broke these graphs up by the predicted modules, so that the response of genes in WT and KO can be compared in those modules for which we predicted that the regulator regulates the module.