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 >4x |
Module 574 |
| General Properties | |
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| Below we list the number of gene sets from which the module was composed was originally composed, and the number of genes and experiments that it contains. Clicking on the number of genes will display a detailed list of all the genes in the module. Clicking on the number of experiments will display a detailed list of all the experiments in the module. | |
| Num gene sets: | 2 |
| Num genes: | 14 (see 95 additional genes for this module) |
| Num experiments: | 34 (15 induced, 19 repressed) |
| Gene sets | |
|---|---|
| Below we list the gene sets from which the module was originally composed. Clicking on a gene set will display all the genes associated with that gene set. Also listed are all the other modules in which the gene set participates. | |
| drug resistance | 574 |
| cysteine protease inhibitor activity | 574 |
| Enriched clinical annotations | ||||
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| For each of the clinical annotations, we tested whether it was enriched in the set of experiments in which the module is significantly induced (or repressed). Below we list all such annotations that were enriched in this module with an FDR corrected p-value of 0.05 ('P-value' column), along with the number ('Hits' column) of induced (or repressed) experiments in which they appear. We also show the fraction of experiments with the given annotation that are included in this module ('Hits (%)' column). Rows that correspond to annotations that were enriched in the induced experiments of the module have a red background, while rows corresponding to annotations enriched in the repressed experiments have a green background. For each annotation, we also list the other modules in which it was enriched. | ||||
| Clinical annotation | P-value | Hits | Hits(%) | Modules |
| Macrophages | 8.50e-05 | 6 | 31.578 | 3 4 8 9 15 16 17 18 21 22 28 31 32 36 37 39 42 48 50 52 53 54 56 57 61 62 69 72 73 74 77 82 83 86 87 91 95 98 102 105 108 114 116 118 119 123 124 125 126 136 143 144 145 150 151 152 158 159 161 163 167 169 171 177 179 188 197 198 208 210 212 219 223 226 233 237 238 239 243 244 252 254 255 263 264 265 273 275 278 280 281 289 292 293 300 301 302 303 307 308 312 315 317 319 320 321 323 332 337 344 345 346 352 361 363 367 371 375 376 378 397 399 403 405 412 414 427 436 438 450 451 456 459 479 485 488 491 494 518 522 532 537 538 550 562 568 574 |
| Salmonella | 0.00014 | 4 | 21.052 | 3 4 6 8 9 15 16 17 18 22 27 28 32 39 42 44 45 46 48 50 52 53 62 64 73 74 75 76 77 79 82 83 84 86 87 91 92 95 98 108 114 116 118 121 123 126 128 151 152 159 163 165 169 170 177 197 198 212 223 233 239 243 252 263 264 265 273 275 280 281 307 309 319 323 346 352 363 370 371 395 414 479 488 491 494 518 537 550 562 568 574 |
| Live bacteria | 0.00030 | 4 | 21.052 | 3 4 6 8 9 15 16 17 18 22 27 28 32 39 42 44 46 48 50 52 53 62 64 73 74 75 76 77 79 82 83 84 86 87 91 95 98 108 114 116 118 121 123 126 151 152 159 163 165 169 177 197 198 212 223 226 243 254 263 264 265 273 275 280 281 307 309 311 312 319 323 336 346 352 363 371 414 449 456 477 479 488 491 494 518 537 550 554 562 568 574 |
| Enriched GO annotations | ||||
|---|---|---|---|---|
| For each GO annotation, we tested whether it was enriched in the set of genes of the module. Below we list all such annotations that were enriched in this module with an FDR corrected p-value of 0.05 ('P-value' column), along with the number ('Hits' column) of genes in which they appear. We also show the fraction of genes with the given GO annotation that are included in this module ('Hits (%)' column). | ||||
| GO annotation | P-value | Hits | Hits(%) | |
| cysteine protease inhibitor activity | 1.01e-20 | 8 | 57.142 | |
| protease inhibitor activity | 1.42e-13 | 8 | 57.142 | |
| enzyme inhibitor activity | 2.60e-12 | 8 | 57.142 | |
| enzyme regulator activity | 1.74e-10 | 9 | 64.285 | |
| uptake permease activity | 8.11e-09 | 5 | 35.714 | |
| permease activity | 4.75e-08 | 5 | 35.714 | |
| response to drug | 2.27e-06 | 6 | 42.857 | |
| ion transporter activity | 9.50e-06 | 5 | 35.714 | |
| Visual display | |||||||||
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| Below is a visual display of the module. Shown are those arrays in which the module's genes significantly change, and the direction of change (induction/repression) in each array is indicated (middle, labeled 'Module changes'; red/green row). The arrays that correspond to the significant clinical attributes are also shown (top; brown rows). The gene sets that compose the module are also shown (left) along with an indication of the membership of the module genes in these gene sets. | |||||||||
| You can also view the images within GeneXPress by loading the module gxp file file. | |||||||||
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