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 >4x |
Module 225 |
| General Properties | |
|---|---|
| Below we list the number of gene sets from which the module was composed was originally composed, and the number of genes and experiments that it contains. Clicking on the number of genes will display a detailed list of all the genes in the module. Clicking on the number of experiments will display a detailed list of all the experiments in the module. | |
| Num gene sets: | 3 |
| Num genes: | 9 (see 151 additional genes for this module) |
| Num experiments: | 15 (11 induced, 4 repressed) |
| Gene sets | |
|---|---|
| Below we list the gene sets from which the module was originally composed. Clicking on a gene set will display all the genes associated with that gene set. Also listed are all the other modules in which the gene set participates. | |
| voltage_gated potassium channel complex | |
| inotropic glutamate receptor activity | 225 380 |
| cation transport | 225 380 |
| Enriched clinical annotations | ||||
|---|---|---|---|---|
| For each of the clinical annotations, we tested whether it was enriched in the set of experiments in which the module is significantly induced (or repressed). Below we list all such annotations that were enriched in this module with an FDR corrected p-value of 0.05 ('P-value' column), along with the number ('Hits' column) of induced (or repressed) experiments in which they appear. We also show the fraction of experiments with the given annotation that are included in this module ('Hits (%)' column). Rows that correspond to annotations that were enriched in the induced experiments of the module have a red background, while rows corresponding to annotations enriched in the repressed experiments have a green background. For each annotation, we also list the other modules in which it was enriched. | ||||
| Clinical annotation | P-value | Hits | Hits(%) | Modules |
| Liver non-tumor | 0.00021 | 3 | 75 | 1 2 5 6 8 9 10 11 12 15 18 19 23 24 26 27 33 34 38 40 41 43 44 45 46 47 48 49 53 54 55 57 58 60 63 64 66 73 75 76 78 79 84 85 88 92 93 94 95 96 98 99 100 101 106 107 108 109 112 117 118 121 122 123 124 125 128 129 130 131 132 134 135 137 140 146 154 158 162 163 164 165 170 171 172 176 180 184 185 190 191 193 197 198 199 205 207 208 209 212 213 220 221 223 225 227 234 235 236 238 239 241 244 247 248 249 252 253 257 259 262 263 265 276 283 286 287 288 289 292 294 295 297 301 302 305 306 309 310 315 319 320 321 324 327 335 337 342 343 345 349 353 354 357 364 370 372 373 375 385 397 401 403 404 405 410 415 417 422 423 424 426 431 434 436 437 440 445 452 456 458 461 468 469 470 474 478 479 481 484 485 486 494 495 496 505 506 521 523 528 529 536 544 545 546 556 566 |
| Enriched GO annotations | ||||
|---|---|---|---|---|
| For each GO annotation, we tested whether it was enriched in the set of genes of the module. Below we list all such annotations that were enriched in this module with an FDR corrected p-value of 0.05 ('P-value' column), along with the number ('Hits' column) of genes in which they appear. We also show the fraction of genes with the given GO annotation that are included in this module ('Hits (%)' column). | ||||
| GO annotation | P-value | Hits | Hits(%) | |
| monovalent inorganic cation transport | 1.96e-14 | 8 | 88.888 | |
| ion transport | 4.64e-14 | 9 | 100 | |
| ion channel activity | 1.78e-13 | 8 | 88.888 | |
| glutamate channel activity | 3.85e-13 | 5 | 55.555 | |
| cation transport | 5.42e-13 | 8 | 88.888 | |
| potassium ion transport | 4.86e-11 | 6 | 66.666 | |
| glutamate signaling pathway | 5.39e-11 | 4 | 44.444 | |
| voltage-gated ion channel activity | 1.05e-10 | 6 | 66.666 | |
| potassium channel activity | 4.62e-10 | 5 | 55.555 | |
| channel/pore class transporter activity | 1.74e-09 | 8 | 88.888 | |
| glutamate receptor activity | 3.34e-09 | 5 | 55.555 | |
| synaptic transmission | 1.54e-07 | 5 | 55.555 | |
| porin activity | 1.40e-05 | 5 | 55.555 | |
| Visual display | |||||||||
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| Below is a visual display of the module. Shown are those arrays in which the module's genes significantly change, and the direction of change (induction/repression) in each array is indicated (middle, labeled 'Module changes'; red/green row). The arrays that correspond to the significant clinical attributes are also shown (top; brown rows). The gene sets that compose the module are also shown (left) along with an indication of the membership of the module genes in these gene sets. | |||||||||
| You can also view the images within GeneXPress by loading the module gxp file file. | |||||||||
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