| | ||||
 |
|
|||
 >4x |
Module 369 |
| General Properties | |
|---|---|
| Below we list the number of gene sets from which the module was composed was originally composed, and the number of genes and experiments that it contains. Clicking on the number of genes will display a detailed list of all the genes in the module. Clicking on the number of experiments will display a detailed list of all the experiments in the module. | |
| Num gene sets: | 2 |
| Num genes: | 8 (see 30 additional genes for this module) |
| Num experiments: | 21 (13 induced, 8 repressed) |
| Gene sets | |
|---|---|
| Below we list the gene sets from which the module was originally composed. Clicking on a gene set will display all the genes associated with that gene set. Also listed are all the other modules in which the gene set participates. | |
| tumor necrosis factor receptor binding | 369 426 |
| Shipp02 4 | 369 426 |
| Enriched clinical annotations | ||||
|---|---|---|---|---|
| For each of the clinical annotations, we tested whether it was enriched in the set of experiments in which the module is significantly induced (or repressed). Below we list all such annotations that were enriched in this module with an FDR corrected p-value of 0.05 ('P-value' column), along with the number ('Hits' column) of induced (or repressed) experiments in which they appear. We also show the fraction of experiments with the given annotation that are included in this module ('Hits (%)' column). Rows that correspond to annotations that were enriched in the induced experiments of the module have a red background, while rows corresponding to annotations enriched in the repressed experiments have a green background. For each annotation, we also list the other modules in which it was enriched. | ||||
| Clinical annotation | P-value | Hits | Hits(%) | Modules |
| Unstimulated immune cells | 1.04e-06 | 6 | 46.153 | 16 27 31 37 61 69 73 84 87 114 121 123 126 128 134 136 151 169 170 171 179 197 223 254 255 263 265 288 292 300 303 308 312 317 319 345 369 375 378 399 405 412 433 436 439 456 459 488 491 521 522 532 537 538 550 568 |
| PBMC | 4.16e-05 | 6 | 75 | 37 46 64 69 75 79 84 92 97 108 119 121 128 136 161 169 170 171 174 179 182 208 210 216 223 254 255 261 263 280 292 300 303 308 312 317 345 358 369 375 376 378 399 433 436 439 456 459 481 488 521 522 525 531 532 537 541 544 554 562 |
| Stimulate immune cells | 9.15e-05 | 5 | 62.5 | 5 15 31 37 46 61 64 69 75 76 79 84 92 97 108 119 121 123 124 126 128 136 161 169 170 171 174 179 182 208 223 237 254 255 261 263 280 289 292 300 301 303 308 312 317 345 358 369 375 376 378 399 433 436 439 456 459 481 488 521 522 525 531 532 537 538 541 544 554 562 |
| Monocytes | 0.00010 | 7 | 87.5 | 4 15 27 31 37 61 63 65 69 73 79 82 85 86 87 92 98 99 108 114 117 119 120 121 123 124 126 128 136 138 151 169 171 173 174 175 177 179 182 197 199 208 216 223 237 243 247 248 250 254 255 259 263 264 265 267 273 280 289 292 300 303 308 312 316 317 328 340 341 345 347 358 369 375 376 378 399 403 407 411 414 433 436 439 451 456 459 466 481 488 491 500 518 522 525 531 532 537 538 539 544 562 568 |
| Enriched GO annotations | ||||
|---|---|---|---|---|
| For each GO annotation, we tested whether it was enriched in the set of genes of the module. Below we list all such annotations that were enriched in this module with an FDR corrected p-value of 0.05 ('P-value' column), along with the number ('Hits' column) of genes in which they appear. We also show the fraction of genes with the given GO annotation that are included in this module ('Hits (%)' column). | ||||
| GO annotation | P-value | Hits | Hits(%) | |
| tumor necrosis factor receptor binding | 2.45e-07 | 3 | 37.5 | |
| cytokine activity | 3.75e-05 | 3 | 37.5 | |
| Visual display | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Below is a visual display of the module. Shown are those arrays in which the module's genes significantly change, and the direction of change (induction/repression) in each array is indicated (middle, labeled 'Module changes'; red/green row). The arrays that correspond to the significant clinical attributes are also shown (top; brown rows). The gene sets that compose the module are also shown (left) along with an indication of the membership of the module genes in these gene sets. | |||||||||
| You can also view the images within GeneXPress by loading the module gxp file file. | |||||||||
|
|||||||||
