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 >4x |
Module 394 |
| General Properties | |
|---|---|
| Below we list the number of gene sets from which the module was composed was originally composed, and the number of genes and experiments that it contains. Clicking on the number of genes will display a detailed list of all the genes in the module. Clicking on the number of experiments will display a detailed list of all the experiments in the module. | |
| Num gene sets: | 2 |
| Num genes: | 7 (see 98 additional genes for this module) |
| Num experiments: | 31 (19 induced, 12 repressed) |
| Gene sets | |
|---|---|
| Below we list the gene sets from which the module was originally composed. Clicking on a gene set will display all the genes associated with that gene set. Also listed are all the other modules in which the gene set participates. | |
| Terpenoid_biosynthesis | 394 509 |
| glycosaminoglycan metabolism | 394 509 |
| Enriched clinical annotations | ||||
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| For each of the clinical annotations, we tested whether it was enriched in the set of experiments in which the module is significantly induced (or repressed). Below we list all such annotations that were enriched in this module with an FDR corrected p-value of 0.05 ('P-value' column), along with the number ('Hits' column) of induced (or repressed) experiments in which they appear. We also show the fraction of experiments with the given annotation that are included in this module ('Hits (%)' column). Rows that correspond to annotations that were enriched in the induced experiments of the module have a red background, while rows corresponding to annotations enriched in the repressed experiments have a green background. For each annotation, we also list the other modules in which it was enriched. | ||||
| Clinical annotation | P-value | Hits | Hits(%) | Modules |
| Skin | 2.54e-06 | 5 | 41.666 | 197 302 318 320 394 432 488 509 510 572 |
| Serum response | 6.19e-05 | 3 | 25 | 318 394 432 509 |
| Fibroblasts | 8.85e-05 | 4 | 33.333 | 197 302 318 320 394 432 509 510 572 |
| Cell line | 0.00014 | 8 | 66.666 | 3 9 14 18 52 54 57 85 118 119 124 139 147 153 161 178 180 192 195 198 199 227 244 252 256 279 283 302 315 321 333 334 335 356 362 394 397 403 405 406 418 426 427 444 451 455 480 485 492 493 503 505 507 513 516 561 576 |
| HCC | 0.00030 | 6 | 31.578 | 3 8 9 10 15 16 17 18 19 23 24 27 40 41 43 44 47 48 49 52 53 54 55 57 58 63 64 67 72 76 78 88 90 92 93 95 98 99 101 106 108 117 118 123 125 129 130 132 135 137 140 143 144 154 158 162 163 164 165 171 172 180 184 185 189 190 193 198 205 207 208 209 212 221 223 234 235 239 247 249 251 252 257 259 263 286 289 292 293 294 295 305 306 309 310 337 342 343 345 353 354 367 372 373 375 391 394 397 415 421 422 424 432 436 440 452 458 469 470 474 478 479 481 486 495 505 506 507 510 514 515 523 526 536 543 544 545 553 566 573 |
| Enriched GO annotations | ||||
|---|---|---|---|---|
| For each GO annotation, we tested whether it was enriched in the set of genes of the module. Below we list all such annotations that were enriched in this module with an FDR corrected p-value of 0.05 ('P-value' column), along with the number ('Hits' column) of genes in which they appear. We also show the fraction of genes with the given GO annotation that are included in this module ('Hits (%)' column). | ||||
| GO annotation | P-value | Hits | Hits(%) | |
| isoprenoid biosynthesis | 8.47e-09 | 3 | 42.857 | |
| cholesterol biosynthesis | 1.92e-07 | 3 | 42.857 | |
| glycosaminoglycan metabolism | 2.86e-07 | 3 | 42.857 | |
| lipid biosynthesis | 4.45e-06 | 3 | 42.857 | |
| lipid metabolism | 6.37e-06 | 4 | 57.142 | |
| regulation of biosynthesis | 9.20e-06 | 3 | 42.857 | |
| catalytic activity | 6.11e-05 | 7 | 100 | |
| Visual display | |||||||||
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| Below is a visual display of the module. Shown are those arrays in which the module's genes significantly change, and the direction of change (induction/repression) in each array is indicated (middle, labeled 'Module changes'; red/green row). The arrays that correspond to the significant clinical attributes are also shown (top; brown rows). The gene sets that compose the module are also shown (left) along with an indication of the membership of the module genes in these gene sets. | |||||||||
| You can also view the images within GeneXPress by loading the module gxp file file. | |||||||||
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