Module 348

Jump to: General properties | Gene sets | Enriched clinical annotations | Enriched Go annotations | Visual display

General Properties
Below we list the number of gene sets from which the module was composed was originally composed, and the number of genes and experiments that it contains. Clicking on the number of genes will display a detailed list of all the genes in the module. Clicking on the number of experiments will display a detailed list of all the experiments in the module.
Num gene sets:	3
Num genes:	8 (see 3 additional genes for this module)
Num experiments:	201 (76 induced, 125 repressed)

Jump to: General properties | Gene sets | Enriched clinical annotations | Enriched Go annotations | Visual display

Gene sets
Below we list the gene sets from which the module was originally composed. Clicking on a gene set will display all the genes associated with that gene set. Also listed are all the other modules in which the gene set participates.
Chen02 10	348 449 541
secondary metabolism	258 348 449 541
Pollack99 25	258 348 449 541

Jump to: General properties | Gene sets | Enriched clinical annotations | Enriched Go annotations | Visual display

Enriched clinical annotations
For each of the clinical annotations, we tested whether it was enriched in the set of experiments in which the module is significantly induced (or repressed). Below we list all such annotations that were enriched in this module with an FDR corrected p-value of 0.05 ('P-value' column), along with the number ('Hits' column) of induced (or repressed) experiments in which they appear. We also show the fraction of experiments with the given annotation that are included in this module ('Hits (%)' column). Rows that correspond to annotations that were enriched in the induced experiments of the module have a red background, while rows corresponding to annotations enriched in the repressed experiments have a green background. For each annotation, we also list the other modules in which it was enriched.
Clinical annotation	P-value	Hits	Hits(%)	Modules
Activated B like	4.45e-09	11	14.473	2 5 6 16 27 33 37 38 44 45 46 52 53 55 60 63 64 69 75 76 79 84 85 88 97 108 117 118 119 128 134 136 145 169 170 171 172 174 179 182 188 193 199 204 208 223 238 241 255 258 259 261 263 288 289 291 292 300 301 311 317 345 348 358 361 367 375 378 399 436 449 459 502 513 522 525 532 556 562
CLL	5.02e-08	15	12	3 5 8 16 17 18 21 37 52 53 54 56 57 61 64 69 72 76 79 84 97 98 102 105 118 119 124 125 126 128 136 145 156 158 161 169 170 171 179 182 187 188 197 198 210 212 219 236 237 238 240 244 245 252 254 255 258 261 292 300 301 302 303 308 312 313 315 317 337 344 345 348 358 361 378 399 403 436 451 456 459 485 502 513 522 525 531 532 537 547 554 562 573
DLBCL tissue	7.97e-08	20	26.315	33 37 47 60 69 70 76 79 84 97 118 120 128 136 138 145 169 170 171 174 175 179 182 188 201 204 208 210 211 214 237 238 241 255 258 261 291 292 300 301 317 329 345 348 358 361 378 387 398 399 436 449 456 459 466 468 512 513 522 525 532 562
COID	8.58e-08	10	8	1 3 5 6 7 8 10 11 15 17 18 22 25 27 34 36 38 41 42 44 47 52 54 58 62 66 67 68 74 76 77 79 84 92 94 100 104 105 107 108 109 113 116 118 119 121 122 126 128 129 130 131 137 139 143 144 148 152 153 154 164 165 169 170 171 172 174 177 180 181 191 194 204 208 209 213 215 223 230 234 235 241 250 254 262 263 270 275 291 292 293 297 298 307 311 312 316 321 324 326 327 342 345 348 357 373 379 381 382 385 390 391 401 406 412 413 426 431 435 436 439 443 450 461 462 464 467 473 479 483 488 513 514 526 538 540 543 549 564 573 578
DLBCL tissue and cell line	2.13e-07	20	26.315	33 37 47 52 61 69 70 76 79 84 97 118 120 128 136 138 145 169 170 174 175 179 182 188 201 204 208 210 211 214 237 238 241 255 258 261 291 292 300 301 317 329 345 348 358 361 378 387 398 399 436 449 456 459 466 468 512 513 522 525 532 562
Breast cell line	1.00e-05	12	9.6	0 1 3 14 15 18 26 30 33 34 44 45 47 52 63 68 71 79 85 99 107 119 122 128 134 139 146 154 170 171 172 178 180 186 191 193 199 207 208 258 262 279 288 292 293 297 321 324 325 331 334 341 342 345 348 357 361 362 389 411 418 424 432 455 467 478 485 509 511 513 516 526 561
Lymphoma tissue or cell line	1.36e-05	20	26.315	33 37 61 69 70 79 97 118 120 128 136 138 145 169 170 174 175 179 182 188 201 204 214 237 238 241 255 258 261 278 291 292 301 317 329 345 348 358 361 378 387 398 399 436 456 459 468 512 513 525 532 562
Dead - B lymphoma	4.27e-05	10	13.157	33 37 69 70 76 79 84 97 118 120 128 136 138 145 169 170 174 175 179 182 188 201 204 208 210 214 237 238 241 255 258 261 291 292 300 301 317 329 345 348 358 361 378 387 436 459 468 512 513 522 525 532 562
After chemo (doxo, BC)	9.64e-05	6	7.894	1 2 5 6 11 12 23 24 26 27 33 38 44 46 47 55 60 63 64 66 75 84 88 100 107 112 117 122 129 137 139 161 171 172 180 206 207 208 209 211 213 220 234 258 289 292 320 324 342 345 348 385 389 424 436 461 467 478 513
Rai=2	0.00021	4	3.2	57 119 126 145 169 188 238 254 301 308 312 315 348 358 361 399 451 456 537 554

Jump to: General properties | Gene sets | Enriched clinical annotations | Enriched Go annotations | Visual display

Enriched GO annotations

For each GO annotation, we tested whether it was enriched in the set of genes of the module. Below we list all such annotations that were enriched in this module with an FDR corrected p-value of 0.05 ('P-value' column), along with the number ('Hits' column) of genes in which they appear. We also show the fraction of genes with the given GO annotation that are included in this module ('Hits (%)' column).

Jump to: General properties | Gene sets | Enriched clinical annotations | Enriched Go annotations | Visual display

Visual display
Below is a visual display of the module. Shown are those arrays in which the module's genes significantly change, and the direction of change (induction/repression) in each array is indicated (middle, labeled 'Module changes'; red/green row). The arrays that correspond to the significant clinical attributes are also shown (top; brown rows). The gene sets that compose the module are also shown (left) along with an indication of the membership of the module genes in these gene sets.
You can also view the images within GeneXPress by loading the module gxp file file.
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